Request for participation in multisector thyroid hormone survey & historical control data collection

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The Health and Environmental Sciences Institute (HESI) Developmental and Reproductive Toxicology (DART) Technical Committee Thyroid Hormone Workgroup, in collaboration with the European Teratology Society (ETS) Thyroid Hormone Task Force, has initiated a comprehensive effort to survey and collect historical data for thyroid hormones measurements from nonclinical studies. Regulatory test guideline requirements for the measurement of thyroid hormones are already in place for several study types, and deliberations continue for other guidelines. This HESI DART-ETS joint effort aims to provide clarification and guidance regarding the collection, assessment and interpretation of thyroid hormone data for regulatory toxicology and risk assessment. The data collected will be anonymously archived in a database that will ultimately be available for public use and incorporated into a workshop planned for Spring 2019. The facility/laboratory, assay and strain-specific data collected will ultimately contribute to improved data interpretation, the establishment of biologically relevant ranges for each assessment and recommendations for best practices for thyroid assessment.

If your organization conducts these assays and you are interested participating in the survey and contributing to the data collection effort, please contact Connie Chen ( for more information.

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