Research Scientist - Charles River, Horsham, PA

Req ID #: 41289

Location: Horsham, PA, US, 19044

For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Charles River Horsham, our Pennsylvania location, was opened in 1979 under the name of Argus Research Laboratories and became part of Charles River in 2001. We specialize in Reproductive and Developmental Toxicology (DART), Juvenile Toxicology, Neurobehavioral Toxicology, Phototoxicology and Cellular Therapeutic Safety. The internationally-recognized scientists at this facility have unmatched expertise in DART and Phototoxicology and the facility is rapidly developing recognition for its capabilities in Cellular Therapeutic safety Evaluations. Horsham also holds the most extensive DART historical control database available in the industry.   Horsham is ideally located just north of historic Philadelphia, Pennsylvania and its many historic attractions, sports activities, colleges and universities, concerts and shopping. We are just a couple of hours drive to Pennsylvania’s mountains and the beaches of New Jersey, Delaware, and Maryland and, via car or Amtrak, to New York City and Washington, D.C.


Serve as a scientist and study director in the conduct of preclinical reproductive and developmental toxicology (DART) research studies of moderate to high complexity.


  • Perform responsibilities as a Study Director for regulatory, exploratory, and investigative reproductive toxicology studies, including study design and protocol development, as well as data evaluation and reporting in a GLP environment.
  • Function independently as a study director in compliance with GLP regulations. Serve as a key contributor and a specialty area expert in reproductive and developmental toxicology, preferably with a strong background in physiology, anatomy, embryology and/or embryo-fetal development.
  • Function independently as a single point of contact for the planning, execution, management, and reporting of preclinical studies.
  • Coordinate all phases of the study planning process with appropriate departments and Test Sites.
  • Implement new approaches, processes, technologies as part of DART evaluations.
  • Generate high-quality protocols, amendments and reports.
  • Review, interpret, integrate and present data on assigned studies.
  • Provide technical and scientific guidance to the research staff.
  • Review reports for peers as needed.
  • Attend scientific meetings, conferences and training courses to enhance job and professional skills.
  • May supervise research and/or scientific staff, as appropriate, for scope of responsibilities.


Education: Bachelor’s degree (B.S./B.A.) or equivalent in a scientific related discipline. Masters or Ph.D. in Toxicology, Developmental Biology, Pharmacology, Physiology, or similar field strongly preferred.


  • Must have expertise in reproduction and/or embryo-fetal development with 2 to 5 years’ post-degree experience as an investigator or study director.
  • Acknowledged professional expertise and reputation at the regional/national level, as evidenced by published record, professional meeting presentations, participation in review and input of regulatory guidances, and/or professional honors.
  • In vivo laboratory experience required. Ability to work in matrixed environment, across multiple disciplines and departments, managing multiple projects simultaneously. Effective written and verbal communication skills required.
  • Thorough understanding of GLP regulatory requirements, and various DART testing guidelines.
  • Knowledge of standard operating and IACUC procedures. Demonstrated leadership skills, experience with client interactions and business development.
  • Ability to handle multiple projects, prioritize work and meet deadlines.
  • Proficiency in the use of standard software including Microsoft Excel, Word, PowerPoint, etc. and with standard laboratory calculations.

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market.  Each year approximately 120 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 13,000 employees within 80 facilities in 23 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges.  Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 80% of the drugs approved by the FDA in 2017.

For more information, please visit

Equal Employment Opportunity
Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet

Nearest Major Market: Philadelphia 
Job Segment: Research Scientist, Scientific, Toxicology, Biotech, Science, Engineering, Research

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