Call for Papers: Two Special Issues of DNTS Journal Neurotoxicology and Teratology (Opioids / Non-Mammalian Models)

Please see the two calls for papers below, from our sister society, the Developmental Neurotoxicology Society (DNTS):

NTT Call for Papers: Understanding Opioids within Developmental Context

The recent explosion of opioid addiction and its public health consequences have overwhelmed treatment and community resources. As the population of chronic opioid users expands, it has become clear that the impact of opioid use during different developmental windows may have distinct consequences. Such developmental periods certainly include fetal exposure, which has dramatically increased over the past decade; but also includes use during adolescence and in elderly populations. In addition to the direct effects of opioids, it is now recognized that elevated risk of certain mental illnesses across development can influence both the incidence of and outcomes associated with opioid use disorder. Moreover, the role of polysubstance use on long-term outcomes associated with opioids must also be considered.

Accordingly, Neurotoxicology and Teratology is organizing a Special Issue on the theme of “Understanding Opioids within a Developmental Context”, which will be co-edited by Drs. Eiden, Byrnes, and Willford. The focus of this special issue is on advancing current understanding of the opioid problem in the context of developmental science, with age as an important variable. Epidemiologic data and treatment options should also be considered within the context of the age-specific effects of opioid exposure.

Submissions may include:

  • Primary data driven reports
  • Critical review papers
  • Prospective/retrospective human studies
  • Empirical in vivo or in vitro studies using laboratory animals or cell culture systems

The following are examples of relevant topics for this Special Issue:

  • Pharmacologic and neurotoxic effects of opioids on age-specific behaviors including pain sensitivity
  • Developmental windows of vulnerability to and long-term consequences of opioid use disorder
  • Clinical care of opioid-exposed neonates in the immediate postpartum period
  • Long-term consequences of prenatal exposure, Neonatal Opioid Withdrawal Syndrome
  • Age-specific epidemiological findings in opioid addiction and therapeutic uses of opioid drugs
  • Normal development of the endogenous opioid system and the disruptive effects of exogenous opioid exposure
  • Neural and/or endocrine mechanisms mediating age differences in the behavioral effects of opioid exposure
  • Age-specific prevention strategies for opioid use disorders and overdose

All submissions to this Special Issue will be fully peer-reviewed, and because Neurotoxicology and Teratology is abstracted and indexed in BIOSIS, Current Contents/Life Sciences, EMBASE, EMBiology, ETOH, Elsevier BIOBASE, MEDLINE®, Science Citation Index, and Scopus, its contents will be available through typical search engines of the medical literature (e.g., PubMed). The Special Issue will also be circulated to all subscribers of the journal and be accessible via ScienceDirect.

This Special Issue will be in the form of a Virtual Special Issue (VSI), which is an approach to publishing Special Issues that allows us to address one of the most common complaints by authors – slow publication speed. With a VSI, accepted manuscripts are published in the first available regular issue, and corresponding authors will receive 50 days free access to the final published version of their manuscript. Thus, authors do not need to wait until all the Special Issue manuscripts are accepted to have their manuscript published. Simultaneously, articles will appear in a VSI section on the Neurotoxicology and Teratology website and on ScienceDirect.

To be considered for inclusion in this Special Issue, please submit your manuscript to Neurotoxicology and Teratology by September 1, 2020, via the electronic submission system (https://www.evise.com/profile/#/NTT/login). Manuscripts should be assigned to the category “VSI: Opioids” at the beginning of the submission process, and a cover letter to the Editor should also specify that the submission is targeted for this issue.

We hope that you will consider this invitation seriously and submit your best work to this issue. Recent trends in scientific publication indicate that articles that appear in special issues receive a great deal of attention and we hope that you will take advantage of this opportunity. If you have any questions, feel free to contact one of the Co-Editors. We look forward to your contributions to this Special Issue.

Thank you.

Special Issue Co-Editors’ Contact Information

Rina D. Eiden, Ph.D. Pennsylvania State University, Email: rina.eiden@psu.edu

Elizabeth M. Byrnes, Ph.D., Tufts University, Email: elizabeth.byrnes@tufts.edu

Jennifer Willford, Ph.D. Slippery Rock State University, Email: jennifer.willford@sru.edu

Neurotoxicology and Teratology Contacts

Jerrold S. Meyer, Ph.D., Special Issues Editor; Email: jmeyer@psych.umass.edu

Gale A. Richardson, Ph.D., Editor-in-Chief; Email: gar@pitt.edu

 

NTT Call for Papers: Leveragaing Non-Mammalian Models for Developmental Neurotoxicity Testing

The developing nervous system is a sensitive target for chemical exposure in both humans and animal models, and early life-stage exposures can lead to long-term effects on motor activity, sensory function, and cognition. Developed and issued by the Organization for Economic Co-operation and Development (OECD), the developmental neurotoxicity (DNT) test guideline (OECD TG 426) is used to assess the potential effects of pre- and postnatal chemical (mainly pesticide) exposure on the morphology and function of the developing nervous system within pre-weaning, adolescent, and young adult rodents. Commonly used strains of rats are preferred for this guideline, and each DNT study requires approximately 640-1200 rats (excluding dams) per chemical.  While DNT data are lacking for tens of thousands of chemicals used in commerce, it is impractical to screen these chemicals using the existing DNT test guideline, as this test relies on a large number of animals and is expensive, low-throughput, and labor-intensive. Therefore, there is a recognized need to rely on cell-based assays and alternative non-mammalian models to support rapid and cost-effective screening and prioritization of chemicals for DNT testing in rodents. Currently, the vast majority of high-throughput screening (HTS) and high-content screening (HCS) assays used for DNT testing utilize cell-free and cell-based methods that model key biological events across a wide range of toxicologically-relevant pathways. However, these assays do not adequately reflect the complex physiology of an intact organism. Therefore, the use of smaller, alternative non-mammalian animal models (such as nematodes, flies, and fish embryos) have been proposed as complementary models to cell-free and cell-based methods, as these models are also suitable for microplate-based HTS/HCS assays and mechanism-based neurotoxicological research.

In order to highlight the use of non-mammalian models for developmental neurotoxicity testing, Neurotoxicology and Teratology is organizing a Special Issue focused on the theme of “Leveraging Non-Mammalian Models for Developmental Neurotoxicity Testing”. We invite all researchers within the field of developmental neurotoxicology to contribute primary data-driven papers or critical review articles. We welcome submissions that highlight the utility of non-mammalian models for 1) testing a wide variety of developmental neurotoxicants – including emerging, understudied contaminants such as flame retardants (brominated and phosphorous) and per- and polyfluoroalkyl substances (PFASs) and 2) uncovering mechanisms underlying environmental chemical-induced neurotoxicity. Non-mammalian models include, but are not limited to, fish (e.g., zebrafish), nematodes (e.g., Caenorhabditis elegans), fruit flies (e.g., Drosophila melanogaster), echinoderms (e.g., sea urchins), and planarians. Ecotoxicology studies in sampled wild animals or targeted exposures directly in the environment will be considered if a clear case can be made for predictive power and human health relevance (e.g., sentinel sampling of amphibian toxicant levels and associated adverse neurological outcomes).

All submissions to this Special Issue will be fully peer-reviewed, and because Neurotoxicology and Teratology is abstracted and indexed in BIOSIS, Current Contents/Life Sciences, EMBASE, EMBiology, ETOH, Elsevier BIOBASE, MEDLINE®, Science Citation Index, and Scopus, its contents will be available through typical search engines of the medical literature (e.g., PubMed). The Special Issue will also be circulated to all subscribers of the journal and be accessible via ScienceDirect.

This Special Issue will be in the form of a Virtual Special Issue (VSI), which is an approach to publishing Special Issues that allows us to address one of the most common complaints by authors – slow publication speed. With a VSI, accepted manuscripts are published in the first available regular issue, and corresponding authors will receive 50 days free access to the final published version of their manuscript. Thus, authors do not need to wait until all the Special Issue manuscripts are accepted to have their manuscript published. Simultaneously, articles will appear in a VSI section on the Neurotoxicology and Teratology website and on ScienceDirect.

To be considered for inclusion in this Special Issue, please submit your manuscript to Neurotoxicology and Teratology by June 1, 2020 via the electronic submission system (https://www.evise.com/profile/#/NTT/login). Manuscripts should be assigned to the category “VSI: Non-Mammalian Models” at the beginning of the submission process, and a cover letter to the Editor should also specify that the submission is targeted for this issue.

We hope that you will consider this invitation seriously and submit your best work to this issue. Recent trends in scientific publication indicate that articles that appear in special issues receive a great deal of attention and we hope that you will take advantage of this opportunity. If you have any questions, please feel free to contact one of the Co-Editors. We look forward to your contributions to this Special Issue.

Thank you,

David C. Volz, Jason Cannon, and Tamara Tal

Special Issue Co-Editors’ Contact Information

David C. Volz, Ph.D. University of California, Riverside, Email: david.volz@ucr.edu; Phone: +1-951-827-4450

Jason Cannon, Ph.D., Purdue University, Email: cannonjr@purdue.edu; Phone: +1-765-494-0794

Tamara Tal, Ph.D., UFZ Helmholtz Center for Environmental Research, Email: tamara.tal@ufz.de; Phone: +49-341-235-1524

Neurotoxicology and Teratology Contacts

Jerrold S. Meyer, Ph.D., Special Issues Editor; Email: jmeyer@psych.umass.edu

Gale A. Richardson, Ph.D., Editor-in-Chief; Email: gar@pitt.edu

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