Recent Publication on COVID-19 Vaccination and Pregnancy

The following is information is being provided through the Society's membership in the Friends of NCBDDD.

UPDATE 8/11/2021

Dear Friends of NCBDDD,

Today, CDC published a new analysis: Receipt of mRNA COVID-19 vaccines preconception and during pregnancy and risk of self-reported spontaneous abortions, CDC v-safe COVID-19 Vaccine Pregnancy Registry 2020-21, showing the cumulative risk of miscarriage after receiving an mRNA COVID-19 vaccine (13%) was similar to previously published estimates (11-16%).  This report included 2,456 pregnant people enrolled in the v-safe pregnancy registry who received at least one dose of an mRNA COVID-19 vaccine just before pregnancy or prior to 20 weeks of pregnancy (as of July 19, 2021). These data do not suggest an increased risk for miscarriage after receiving an mRNA COVID-19 vaccine just before or within the first 20 weeks of pregnancy. These preliminary findings are reassuring and can help inform discussions about COVID-19 vaccination during pregnancy between pregnant people and their healthcare providers.
Growing evidence about the safety and effectiveness of COVID-19 vaccination during pregnancy demonstrates that the benefits of receiving a COVID-19 vaccine outweigh any known or potential risks. CDC recommends that pregnant people should be vaccinated against COVID-19. COVID-19 vaccination is recommended for all people 12 years and older, including people who are pregnant, breastfeeding, trying to get pregnant now, or might become pregnant in the future.
Additionally, we’ve heard reports that clinicians have seen the number of pregnant people infected with COVID-19 rise in the past several weeks. The increased circulation of the highly contagious Delta variant, the low vaccine uptake among pregnant people, and the increased risk of severe illness and pregnancy complications related to COVID-19 infection among pregnant people make vaccination for this population more urgent than ever.
We encourage you to share these preliminary findings and our strengthened recommendation widely with your partners and networks and on your organization’s social media pages. CDC is committed to learning about COVID-19 vaccination during pregnancy and will continue to share new information as it becomes available.
Thank you for your continued partnership and collaboration with CDC.
Karen Remley, MD, MBA, MPH, FAAP
Director, National Center on Birth Defects and Developmental Disabilities
Centers for Disease Control and Prevention
1600 Clifton Road NE, MS S106-4
Atlanta, GA 30329-4018
Office: 404-498-3800

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