Improved quantitative epidemiological/ biostatistical approaches -- Post July 9, 2015

Improved quantitative epidemiological/ biostatistical approaches for assessment of human health effects associated with chemical exposures


Brief description of Research Project: NCEA is responsible for scientific assessment activities related to the health effects of chemical pollutants in the IRIS (Integrated Risk Information System) program, as well as in the development of Integrated Science Assessments for the major air pollutants. These assessments provide key scientific support for EPA policy and regulatory decisions. The assessment activities typically have significant implications for national and international environmental policy development and implementation. This project focuses on developing or adapting advanced approaches in quantitative health risk assessment. Participants will collaborate with EPA scientists on addressing a wide range of quantitative issues that arise in the analysis and interpretation of data for IRIS chemical assessments (see These data may be obtained from epidemiological investigations and laboratory animal bioassays as well as from molecular toxicology/epidemiology, pathway-based biomarker studies or from laboratory studies of mechanisms of toxicity.

Activities may include:

•reviewing these data in order to conduct quantitative analyses on health effects related to exposures to environmental chemicals; •developing statistical models for utilizing multiple streams of data for assessing health risk;

•the quantitative analysis of epidemiological data on environmental and occupational exposure to chemicals;

•the use of Bayesian methods in dose-response analyses. The participant will have opportunities to interact with scientific staff in NCEA and potentially scientists from other EPA Labs, Centers or Offices, and will learn how to synthesize and communicate various kinds of scientific information in health assessment. There is the potential for more than one selection to be made from this postdoctoral position announcement.

Geographical location of position: Research Triangle Park, NC; Arlington, VA

High priority research areas: Human Health Risk Assessment

Scientific project area: IRIS Assessments, IRIS Scientific and Technical Support, Advancing and Transforming Risk Assessment Methods

 Educational requirements: PhD in quantitative epidemiology, biostatistics, applied mathematics or a closely related field.

Specialized training and/or experience preferred: Quantitative epidemiologic analysis; modeling of human health and environmental exposure data; experience in computational statistics; use of bayesian methods.

Projected duration of appointment: 3 years

Paid relocation to EPA work location: Yes

Application Period Open Date: June 15, 2015

Application Period Close Date: July 20, 2015

Scientific contact/Principal Investigator(s): Ravi Subramaniam,, 703-347-8606

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